Old Form of CA-MRSA Is Back, but Worse
United Press International, April 1, 2005
BATH, England, Apr 01, 2005 (United Press
International via COMTEX) -- British researchers said an
antibiotic-resistant bacteria that caused a global infection epidemic
in the 1950s has re-emerged as a community-acquired superbug.
International researchers led by the University of Bath, writing in
the Lancet, said this could mean community-acquired Methicillin-resistant
Staphylococcus Aureus or CA MRSA will spread faster and be more
widespread than previously expected.
First isolated in Australia and Canada in 1953, type 80/81
penicillin-resistant Staphylococcus aureus bacteria caused skin
lesions, sepsis and pneumonia in children and young adults until it
was stopped in the 1960s by the antibiotic methicillin.
Researchers said a new version of 80/81 resistant to methicillin
antibiotics may have evolved from the earlier strain.
The researchers sequenced key genes from saved 80/81 samples and
compared them with the same regions in genes from most common CA MRSAs
found in England and Scotland. Key regions in nearly all of the 80/81
isolates were identical and shared the same highly-virulent toxin,
called Panton-Valentine leucocidin
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